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Provided by: Medscape

Impact of PPIs on Spontaneous Bacterial Peritonitis

Published: Thu, 18 Oct 2018 12:00:00 EDT
In what ways might the dosages of proton pump inhibitors affect the incidence and clinical course of spontaneous bacterial peritonitis?
Liver International

Advance Care Planning in Cognitively Impaired Older Adults

Published: Thu, 18 Oct 2018 12:00:00 EDT
Advance care planning for individuals with cognitive impairment is challenging. This article provides valuable practice pointers for assessment, shared decision-making, and reimbursement.
Journal of the American Geriatrics Society

Costs Associated With Diabetes Among Adult Medicaid Enrollees

Published: Thu, 18 Oct 2018 12:00:00 EDT
This report details state-specific financial burdens of diabetes in the Medicaid population of eight states.
Preventing Chronic Disease

FDA Panel Oks Tegaserod for IBS-C in Women with Low CV Risk

Published: Wed, 17 Oct 2018 19:41:59 EDT
The Gastrointestinal Drugs Advisory Committee of the FDA recommended reintroducing tegaserod maleate for women with irritable bowel syndrome and low cardiovascular risk.
Medscape Medical News
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1 year after FDA snub, advisory committee recommends AcelRx's Dsuvia for approval 10-3

Published: Fri, 12 Oct 2018 21:12:27 +0000
An FDA advisory committee recommended AcelRx's Dsuvia, a sublingual version of sufentanil, for approval in a 10-3 vote. The meeting came exactly one year after the FDA declined to approve the drug.

‘Retina in a dish’ provides new insight into inherited blindness

Published: Fri, 12 Oct 2018 16:59:27 +0000
Mutations in cell proteins known as “splicing factors” can cause the eye disease retinitis pigmentosa, though the exact mechanism behind the problem has been somewhat of a mystery. Scientists at Newcastle University demonstrated that defective splicing factors are unable to correctly proofread the genetic code of retinal cells, resulting in a progressive loss of sight.

Adynxx merges with Alliqua, snagging Nasdaq listing ahead of pain trials

Published: Fri, 12 Oct 2018 12:25:26 +0000
Adynxx is set to gain a Nasdaq listing by merging with Alliqua BioMedical. The reverse merger comes six months after Adynxx committed to advancing pain drug brivoligide, despite the candidate coming up short in a midphase study.

Hoth Therapeutics seeks IPO cash to battle eczema

Published: Fri, 12 Oct 2018 10:07:35 +0000
Hoth Therapeutics has filed to raise around $11 million in a Nasdaq IPO. The tiny offering will equip Hoth to test a topical formulation of the broad-spectrum antibiotic gentamicin in a phase 2 eczema trial.
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