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Provided by: Medscape

WGA Speeds Diagnosis of Devastating Seizure Disorder in Kids

Published: Fri, 17 Aug 2018 09:37:19 EDT
Whole-genome analysis looks more clinically and economically feasible for diagnosing newborns with a rare, but devastating, epilepsy syndrome, new research shows.
Medscape Medical News

Weight Gain Doesn't Diminish Benefits of Giving Up Smoking

Published: Fri, 17 Aug 2018 08:48:40 EDT
Risk for type 2 diabetes rises temporarily for people who gain weight when they quit smoking, but cardiovascular benefit stays steady regardless.
Medscape Medical News

AHA Advisory Recommends Healthy Eating, Not Just Variety

Published: Fri, 17 Aug 2018 08:09:54 EDT
The advice to 'eat a variety of foods' is outdated because studies show a more varied diet often included more unhealthy foods and was not linked with a healthier weight, an AHA advisory reports.
Medscape Medical News

Study Supports Newest Indication for IL6R Blockade in Giant Cell Arteritis

Published: Fri, 17 Aug 2018 07:45:03 EDT
New research confirms the association of a common variant in the gene that encodes the receptor for IL-6 with reduced risk for aortic aneurysm and supports the newest indication for IL6R blockade, giant cell arteritis.
Medscape Medical News
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Realm tanks again as second drug fails phase 2

Published: Tue, 14 Aug 2018 08:55:00 +0000
Realm Therapeutics has reported its second midphase flop of the year. The setback threatens to wipe out Realm’s clinical-phase pipeline, leaving the immunology player with just a preclinical acne asset that features the same active ingredient as the failed programs.

Bioverativ executive Rogerio Vivaldi to helm cell therapy producer Sigilon

Published: Mon, 13 Aug 2018 18:47:47 +0000
Sigilon Therapeutics is bringing on Bioverativ’s chief global therapeutic operations officer, Rogerio Vivaldi, M.D., to serve as its CEO. The change comes as Sigilon plans to move its cell-based therapeutic implants into the clinic for phase 1 trials.

Predicting the risk of heart disease, diabetes and more using millions of gene variants

Published: Mon, 13 Aug 2018 15:45:44 +0000
Scientists led by the Broad Institute have developed a method for scoring disease risk based on data previously generated about five serious conditions and the gene mutations that contribute to them. Among the insights they generated: Up to 25 million Americans face triple the normal risk of coronary artery disease.

Izana starts proof-of-concept trial for spinal arthritis drug

Published: Mon, 13 Aug 2018 13:29:54 +0000
U.K. startup Izana has started recruiting patients into its phase 2a trial of its anti-GM-CSF antibody namilumab in ankylosing spondylitis, a severe form of arthritis affecting the spine.
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